A proteomics landscape of circadian clock in mouse liver

Yunzhi Wang; Lei Song; Mingwei Liu; Rui Ge; Quan Zhou; Wanlin Liu; Ruiyang Li; Jingbo Qie; Bei Zhen; Yi Wang; Fuchu He; Jun Qin; Chen Ding

doi:10.1038/s41467-018-03898-2

Nature Communications (Apr 2018)

A proteomics landscape of circadian clock in mouse liver

Yunzhi Wang,
Lei Song,
Mingwei Liu,
Rui Ge,
Quan Zhou,
Wanlin Liu,
Ruiyang Li,
Jingbo Qie,
Bei Zhen,
Yi Wang,
Fuchu He,
Jun Qin,
Chen Ding

Affiliations

Yunzhi Wang: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, School of Life Sciences, Zhongshan Hospital, Fudan University
Lei Song: School of Life Sciences, Tsinghua University
Mingwei Liu: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences
Rui Ge: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, School of Life Sciences, Zhongshan Hospital, Fudan University
Quan Zhou: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences
Wanlin Liu: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences
Ruiyang Li: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, School of Life Sciences, Zhongshan Hospital, Fudan University
Jingbo Qie: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, School of Life Sciences, Zhongshan Hospital, Fudan University
Bei Zhen: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences
Yi Wang: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences
Fuchu He: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, School of Life Sciences, Zhongshan Hospital, Fudan University
Jun Qin: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, School of Life Sciences, Zhongshan Hospital, Fudan University
Chen Ding: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, School of Life Sciences, Zhongshan Hospital, Fudan University

DOI: https://doi.org/10.1038/s41467-018-03898-2
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 16

Abstract

Read online

As a circadian organ, liver functions are regulated by circadian clock. Here, the authors present a comprehensive proteomics landscape of the mouse liver, including transcription factor binding profiles, phosphorylation and ubiquitylation patterns, nuclear and whole proteome, and the transcriptome.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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