Malaria Journal (Jul 2009)

Invasive <it>Aspergillus fumigatus </it>infection after <it>Plasmodium falciparum </it>malaria in an immuno-competent host: Case report and review of literature

  • Stremmel Wolfgang,
  • Schnabel Philipp A,
  • Eberhardt Ralf,
  • Gotthardt Daniel,
  • Ebinger Damaris,
  • Eckerle Isabella,
  • Junghanss Thomas,
  • Eisenbach Christoph

DOI
https://doi.org/10.1186/1475-2875-8-167
Journal volume & issue
Vol. 8, no. 1
p. 167

Abstract

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Abstract Invasive fungal infection is rarely reported in association with malaria, even though malaria-associated inhibition of phagocyte function is a well-known condition. Invasive aspergillosis is frequently found in severely immuno-compromised patients but not in healthy individuals. Here, a case of pulmonary invasive aspergillosis in a previously healthy patient with severe P. falciparum malaria is presented, who was successfully treated with voriconazol and caspofungin. This is the first survival of malaria-associated invasive aspergillosis.