Journal of Oral Biology and Craniofacial Research (Jul 2022)

Predictors of Extracapsular Spread in T1/T2 Oral Squamous Cell Carcinoma: A retrospective study

  • Sapna Tandon,
  • Rathindra Nath Bera,
  • Akhilesh Kumar Singh,
  • Madan Mishra

DOI
https://doi.org/10.1016/j.jobcr.2022.05.012
Journal volume & issue
Vol. 12, no. 4
pp. 449 – 453

Abstract

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Introduction: In the N0 neck the incidence of ECS might range from 13 to 60%. In this retrospective study we intended at evaluating the primary tumor and nodal characteristics that might influence the presence of ECS in early stage OSCC. Methods: The predictor variables were tumor and nodal features and the incidence of ENE was the outcome. Univariate and multivariate regression models along with ROC curve and Youden's J statistics was used for analysis. A p value < 0.05 was considered statistically significant. Results: The cut off value for DOI was 6.5 mm and LN size was 12.5 mm with overall accuracy of 80.15% and 84.93% respectively. Primary tumor features and LN size was significantly associated with ENE. Discussion: Oral tongue tumors and PNI are independent risk factors for ENE. An elective neck dissection remains the standard of care from both diagnostic and therapeutic viewpoints.

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