Myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccination: A case report

Abstract

Purpose: We report on the case of a 35-year-old man who developed myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccine injection. Observations: A 35-year-old man complained of binocular diplopia one month following ChAdOx1 nCoV-19 vaccination. He had weak infraduction of the left eye. Upper and lower extremity strength was normal on presentation. A serum antiacetylcholine receptor antibody titer was elevated at 1.60 nmol/L. His diplopia improved temporarily following the application of an ice pack for 2 min. Conclusions and importance: This case report describes a rare occurrence of myasthenia gravis with ocular symptoms as a potential complication of ChAdOx1 nCoV-19 vaccination.

Keywords

• ChAdOx1 nCoV-19 vaccine
• Corona virus disease-19
• COVID-19
• Myasthenia gravis with ocular symptoms
• Antiacetylcholine receptor antibody