Research advances of mRNA methylation in kidney diseases

Shi-wen Zhang; Jun-jun Luan; Hua Zhou

doi:10.3969/j.issn.1671-2390.2024.02.009

Linchuang shenzangbing zazhi (Feb 2024)

Research advances of mRNA methylation in kidney diseases

Shi-wen Zhang,
Jun-jun Luan,
Hua Zhou

Affiliations

Shi-wen Zhang: Department of Nephrology, Affiliated Shengjing Hospital, China Medical University, Shenyang 110004, China
Jun-jun Luan: Department of Nephrology, Affiliated Shengjing Hospital, China Medical University, Shenyang 110004, China
Hua Zhou: Department of Nephrology, Affiliated Shengjing Hospital, China Medical University, Shenyang 110004, China

DOI: https://doi.org/10.3969/j.issn.1671-2390.2024.02.009
Journal volume & issue: Vol. 24, no. 2
pp. 143 – 150

Abstract

Read online

Recently mRNA methylation modification has been extensively examined, including N6-methyladenosine (m6A), N5-methylcytidine (m5C) and N1-methyladenosine (m1A). The dynamic reversible biological processes of mRNA methylation modification include the participations of "Writer", "Eraser" and "Reader". Abnormal methylation may lead to the occurrence and development of acute kidney injury (AKI) and chronic kidney disease (CKD). And mRNA methylation modification shall become a practical biomarker for diagnosing and monitoring kidney diseases.

Published in Linchuang shenzangbing zazhi

ISSN: 1671-2390 (Print)
Publisher: Editorial Department of Journal of Clinical Nephrology
Country of publisher: China
LCC subjects: Medicine: Internal medicine
Website: http://www.lcszb.com/indexen.htm

About the journal

Abstract

Keywords