1197 Site-specific anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy via enhancement of T cell penetration and engagement

• Jie Li,
• Jia Wei,
• Qi Xue,
• Tao Shi,
• Yunfeng Pan,
• Hanbing Wang,
• Xueru Song

Affiliations

Jie Li

2State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Nanjing, Jiangsu, China

Jia Wei

3The Comprehensive Cancer Centre of Drum Tower Hospital, Nanjing, Jiangsu, China

Qi Xue

1Department of Thoracic Surgery, Cancer Hospital of Chinese Academy of Medical Science, Beijing, China

Tao Shi

1Nanjing University Medical School Affiliated Drum Tower Hospital, Nanjing, China

Yunfeng Pan

1The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, China., Nanjing, China

Hanbing Wang

1The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, China., Nanjing, China

Xueru Song

3Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China