IMPACT OF IODINE-CONTAINING PUMPKIN OIL ON THE COURSE OF CARDIAC ISCHEMIA IN THE RESIDENTS OF ZAKARPATTYA REGION

Abstract

The purpose of the research was exploration of the impact of the conventional treatment in combination with simvastatin and iodine-containing pumpkin oil “Fortuna vita” on the values of lipid metabolism in cardiac ischemia patients residing in the setting of iodine deficit. The patients were divided into 2 groups: group 1– patients underwent conventional treatment with application of simvastatin of 20mg/day during the whole course of observation; group 2 – same treatment in combination with iodine-containing pumpkin oil “Fortuna vita” of 10ml/day, which contains 200μg of organically combined iodine form. The level of total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL cholesterol) and lowdensity lipoprotein cholesterol (LDL cholesterol) in serum, and aspartate aminotransferase and alanine aminotrasferase in patients before treatment, after 10 days, and after 1 month of treatment was measured. It was determined, that simvastatin is an effective and safe cholesterol-reducing preparation for cardiac ischemia patients which results in reduction of cholesterol level by 18% and LDL by 23% in one month. A combination of simvastatin and iodine-containing pumpkin oil appears more effective, probably because of potentiation of their effects, which also facilitate growth of antiatherogenic HDL and consequently decrease the atherogenicity coefficient. The general clinical state of both groups improved as a result of the treatment, though more so for the patients treated in combination with iodine-containing pumpkin oil. We are inclined to explain this fact by normalization of iodine-thyroid status, and consequently, of the general metabolism of the patients in the setting of ecologic iodine deficit because of iodine-containing fatty acids.

Keywords

• cardiac ischemia
• simvastatin
• cholesterol
• lipoproteins
• iodinecontaining oil