Disease-modifying antirheumatic drugs – Old and new: A brief overview

Abstract

Rheumatological disorders comprise a vast subset of conditions with differing manifestations but overlap in pathogenesis. Disease-modifying antirheumatic drugs (DMARDs) are a diverse group of medications which aim at the various pathogenic factors leading to these disorders. DMARDs are of three broad subtypes: the conventional synthetic DMARDs, the biologicals, and Janus kinase inhibitors. Here, we give a brief overview of the various DMARDs with an emphasis on their practical use.

Keywords

• biologicals
• disease-modifying antirheumatic drugs
• hydroxychloroquine
• methotrexate