Обзор матриц (scaffolds) для стволовых клеток

Abstract

Scaffolds provide a physicochemical and biological three-dimensional micro-environment for cell growth and differentiation, promoting cell adhesion, and migration. The scaffold can also serve as a carrier for the morphogen. Scaffolds should be effective for the transport of nutrients, oxygen and waste. Preferably, a scaffold should be gradually degraded and replaced by the regenerated tissue, while retaining the features of the final tissue structure. Furthermore, it should be biocompatible, non-toxic, and have proper mechanical strength. Presenting an overview of different types of scaffolds used in dentistry.