Persistently elevated intracranial pressure in cryptococcal meningitis– 76 therapeutic lumbar punctures

Samuel Jjunju; Edwin Nuwagira; David B. Meya; Conrad Muzoora

Medical Mycology Case Reports (Jun 2023)

Persistently elevated intracranial pressure in cryptococcal meningitis– 76 therapeutic lumbar punctures

Samuel Jjunju,
Edwin Nuwagira,
David B. Meya,
Conrad Muzoora

Affiliations

Samuel Jjunju: Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda; Research Department, Infectious Disease Institute, Makerere University, Kampala, Uganda; Corresponding author. Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Edwin Nuwagira: Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda; Research Department, Infectious Disease Institute, Makerere University, Kampala, Uganda
David B. Meya: Research Department, Infectious Disease Institute, Makerere University, Kampala, Uganda
Conrad Muzoora: Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda

Journal volume & issue: Vol. 40
pp. 50 – 53

Abstract

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Cryptococcal meningitis still remains the most common form of adult meningitis in sub-Saharan Africa, due to the burden of HIV/AIDS. Increased intracranial pressure (ICP) is a major complication of cryptococcosis and requires aggressive management with therapeutic lumbar punctures (LPs). In this report, we describe a patient with persistently elevated ICP who underwent 76 LPs over 46 days with good outcome. While unusual, this highlights the importance of serial therapeutic LPs.2012 Elsevier Ltd. All rights reserved.

Published in Medical Mycology Case Reports

ISSN: 2211-7539 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General); Science: Biology (General)
Website: https://www.journals.elsevier.com/medical-mycology-case-reports/

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