Effects of inorganic ions, organic particles, blood cells, and cyclic loading on in vitro corrosion of MgAl alloys

Guanqi Liu; Jianmin Han; Ying Li; Yuzhu Guo; Xiaodong Yu; Shenpo Yuan; Zhihua Nie; Chengwen Tan; Chuanbin Guo

Journal of Magnesium and Alloys (Jul 2023)

Effects of inorganic ions, organic particles, blood cells, and cyclic loading on in vitro corrosion of MgAl alloys

Guanqi Liu,
Jianmin Han,
Ying Li,
Yuzhu Guo,
Xiaodong Yu,
Shenpo Yuan,
Zhihua Nie,
Chengwen Tan,
Chuanbin Guo

Affiliations

Guanqi Liu: School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China; Department of Dental Materials, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Peking University School and Hospital of Stomatology, Beijing 100081, China
Jianmin Han: Department of Dental Materials, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Peking University School and Hospital of Stomatology, Beijing 100081, China; Corresponding authors.
Ying Li: School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China; Department of Dental Materials, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Peking University School and Hospital of Stomatology, Beijing 100081, China
Yuzhu Guo: School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China; Department of Dental Materials, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Peking University School and Hospital of Stomatology, Beijing 100081, China
Xiaodong Yu: School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China
Shenpo Yuan: Department of Dental Materials, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Peking University School and Hospital of Stomatology, Beijing 100081, China
Zhihua Nie: School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China
Chengwen Tan: School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China; Corresponding authors.
Chuanbin Guo: Department of Oral and Maxillofacial Surgery, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Peking University School and Hospital of Stomatology, Beijing 100081, China; Corresponding authors.

Journal volume & issue: Vol. 11, no. 7
pp. 2429 – 2441

Abstract

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Recently, magnesium (Mg) alloys have attracted extensive attention as biodegradable implant materials. However, cyclic loading and the corrosive environment of the body are significant challenges for the practical use of alloys, and there are few studies on this topic. In this study, we conducted a four-point bending fatigue test for 86,400 cycles (12 h) in simulated body fluid (SBF), plasma, and whole blood with an AZ series alloy Mg-9Al-0.5Zn-0.27Mn-0.12Ag, to examine the effects of inorganic ions, organic particles, blood cells, and cyclic loading on Mg alloy corrosion. The Mg2+ concentration and solution pH were measured before and after experimentation, and the sample surfaces were characterized by 3D digital microscopy, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS).Our results showed that in the non-loading condition, a porous and weak inorganic product layer (mainly Mg/Ca phosphate and carbonate) formed on the surface of the Mg alloy sample immersed in SBF, which hardly had a protective effect on Mg alloy corrosion. For the samples immersed in plasma, the organic particles promoted the formation of an organic and more compact product layer, which protected the Mg alloy from severe corrosion. For the sample immersed in whole blood, the blood cells affected organic particle deposition on the product layer and thus interfered with the formation of an organic compact product layer, which slightly accelerated the corrosion process. Furthermore, cyclic loading damaged the layer integrity and significantly increased the corrosion rates of all the studied materials compared to the samples not subjected to cyclic loading. Nonetheless, under cyclic loading, blood cells adsorbed on the Mg alloy surfaces, and formed films, which protected the Mg alloy substrate and delayed Mg alloy corrosion.

Published in Journal of Magnesium and Alloys

ISSN: 2213-9567 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology: Mining engineering. Metallurgy
Website: https://www.keaipublishing.com/en/journals/journal-of-magnesium-and-alloys/

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