Communications Biology (Sep 2022)

A functional interaction between liprin-α1 and B56γ regulatory subunit of protein phosphatase 2A supports tumor cell motility

  • Marta Ripamonti,
  • Andrea Lamarca,
  • Norman E. Davey,
  • Diletta Tonoli,
  • Sara Surini,
  • Ivan de Curtis

DOI
https://doi.org/10.1038/s42003-022-03989-3
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 12

Abstract

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Liprin-α1 interacts with and recruits B56γ-PP2A at the front of migrating breast cancer cells, to promote cell protrusion and motility.