Purpura fulminans following immediate bilateral breast reconstruction: A case report and literature review
Matthew R. Zeiderman,
Lauren M. Perry,
Anthony N. Almazan,
David G. Greenhalgh,
Tina L. Palmieri
Affiliations
Matthew R. Zeiderman
Department of Surgery, University of California, Davis, 2335 Stockton Blvd., 5th Floor, Sacramento, CA, 95817, United States; Corresponding author at: Department of Surgery, University of California, Davis, 2335 Stockton Blvd., 5th Floor, Sacramento, CA, 95817, United States.
Lauren M. Perry
Department of Surgery, University of California, Davis, 2335 Stockton Blvd., 5th Floor, Sacramento, CA, 95817, United States
Anthony N. Almazan
Harvard Medical School, 25 Shattuck St., Boston, MA 02115, United States
David G. Greenhalgh
Department of Surgery, University of California, Davis, 2335 Stockton Blvd., 5th Floor, Sacramento, CA, 95817, United States; Shriners Hospitals for Children, Northern California, 2425 Stockton Blvd., Sacramento, CA 95817, United States
Tina L. Palmieri
Department of Surgery, University of California, Davis, 2335 Stockton Blvd., 5th Floor, Sacramento, CA, 95817, United States; Shriners Hospitals for Children, Northern California, 2425 Stockton Blvd., Sacramento, CA 95817, United States
Purpura fulminans (PF) is a rare, rapidly-progressive and life-threatening syndrome characterized by hypercoagulability that results in disseminated intravascular coagulation, microvascular thrombosis, and hemorrhagic infarction of the skin. Acute bacterial infection is the predominant etiology. The pathophysiology of PF results in extensive soft tissue necrosis with cutaneous wound depth mimicking full-thickness burns, limb gangrene requiring amputation, and multi-organ dysfunction syndrome. Consequently, mortality rate is over 50%. In the following case report, we present PF secondary to a complication of implant-based breast reconstruction following mastectomy. We review the management of PF and emphasize the importance of multidisciplinary management of this life-threatening illness.
