Monaldi Archives for Chest Disease (Mar 2022)

Thyroid dysfunction on the heart: clinical effects, prognostic impact and management strategies

  • Giulia Mattesi,
  • Sara Di Michele,
  • Donato Mele,
  • Ilaria Rigato,
  • Riccardo Bariani,
  • Andrea Fiorencis,
  • Marco Previtero,
  • Abdullah Al Sergani,
  • Loira Leoni,
  • Barbara Bauce,
  • Valeria Pergola

DOI
https://doi.org/10.4081/monaldi.2022.2145

Abstract

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Thyroid hormones have a considerable influence on cardiac function and structure. There are direct and indirect effects of thyroid hormone on the cardiovascular system, which are prominent in both hypothyroidism and hyperthyroidism. In this review, we discuss how thyroid dysfunction impacts cardiovascular pathophysiology and the underlying molecular mechanisms.

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