IRF8 is crucial for the nicotine withdrawal-induced hyperalgesia in mice

Guo Lina; Zhang Yang; Wang Jinping; Qi Yingying; Zhang Zongwang

doi:10.1515/tnsci-2020-0139

Translational Neuroscience (Sep 2020)

IRF8 is crucial for the nicotine withdrawal-induced hyperalgesia in mice

Guo Lina,
Zhang Yang,
Wang Jinping,
Qi Yingying,
Zhang Zongwang

Affiliations

Guo Lina: Department of Anesthesiology, Liaocheng People’s Hospital, Cheeloo College of Medicine, Shandong University, Liaocheng, 252000, Shandong, China
Zhang Yang: Department of Anesthesiology, Liaocheng People’s Hospital, No. 67 of Dongchang West Road, Liaocheng, 252000, Shandong, China
Wang Jinping: Department of Anesthesiology, Liaocheng People’s Hospital, No. 67 of Dongchang West Road, Liaocheng, 252000, Shandong, China
Qi Yingying: Department of Anesthesiology, Liaocheng People’s Hospital, No. 67 of Dongchang West Road, Liaocheng, 252000, Shandong, China
Zhang Zongwang: Department of Anesthesiology, Liaocheng People’s Hospital, Cheeloo College of Medicine, Shandong University, Liaocheng, 252000, Shandong, China

DOI: https://doi.org/10.1515/tnsci-2020-0139
Journal volume & issue: Vol. 11, no. 1
pp. 283 – 293

Abstract

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Interferon regulatory factor 8 (IRF8) is involved in the pathogenesis of neuropathic pain. However, whether and how IRF8 can regulate the nicotine withdrawal (NTW)-induced hyperalgesia has not been clarified.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

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Abstract

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