Проблемы особо опасных инфекций (Mar 2013)
Experimental Technology for O-Antigens Production of Non-Toxigenic Strains of <I>Vibrio cholerae</I>
Abstract
Determined are the key bio-kinetic indexes of submerged cultivation of Vibrio cholerae non-toxigenic strains, producers of O-antigens. Evaluated is the technology of O-antigen concentration using tangential ultrafiltration technique. The results suggest the principal possibility of using these strains for biologically safe production of chemical cholera vaccines.
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