Scientific Reports (Apr 2022)

Coronavirus disease-related in-hospital mortality: a cohort study in a private healthcare network in Brazil

  • Helidea de Oliveira Lima,
  • Leopoldo Muniz da Silva,
  • Arthur de Campos Vieira Abib,
  • Leandro Reis Tavares,
  • Daniel Wagner de Castro Lima Santos,
  • Ana Claudia Lopes Fernandes de Araújo,
  • Laise Pereira Moreira,
  • Saullo Queiroz Silveira,
  • Vanessa de Melo Silva Torres,
  • Deborah Simões,
  • Ramiro Arellano,
  • Anthony M.-H. Ho,
  • Glenio B. Mizubuti

DOI
https://doi.org/10.1038/s41598-022-10343-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Abstract COVID-19-related in-hospital mortality has been reported at 30.7–47.3% in Brazil, however studies assessing exclusively private hospitals are lacking. This is important because of significant differences existing between the Brazilian private and public healthcare systems. We aimed to determine the COVID-19-related in-hospital mortality and associated risk factors in a Brazilian private network from March/2020 to March/2021. Data were extracted from institutional database and analyzed using Cox regression model. Length of hospitalization and death-related factors were modeled based on available independent variables. In total, 38,937 COVID-19 patients were hospitalized of whom 3058 (7.8%) died. Admission to the intensive care unit occurred in 62.5% of cases, and 11.5% and 3.8% required mechanical ventilation (MV) and renal replacement therapy (RRT), respectively. In the adjusted model, age ≥ 61 years-old, comorbidities, and the need for MV and/or RRT were significantly associated with increased mortality (p < 0.05). Obesity and hypertension were associated with the need for MV and RRT (p < 0.05).