Case Reports in Oncology (Mar 2021)

Giant Benign Mammary Phyllodes Tumor: Report of a Case and Review of the Literature

  • Ricardo Fernández-Ferreira,
  • Andrés Arroyave-Ramírez,
  • Daniel Motola-Kuba,
  • Gabriela Alvarado-Luna,
  • Ileana Mackinney-Novelo,
  • Román Segura-Rivera

DOI
https://doi.org/10.1159/000510741
Journal volume & issue
Vol. 14, no. 1
pp. 123 – 133

Abstract

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Phyllodes tumor of the breast is an infrequently encountered fibroepithelial neoplasm, which accounts for 0.3–1% of all tumors. Few case reports have described the occurrence of giant phyllodes tumor. To our knowledge, about 20% of phyllodes tumors would be considered giant benign. Complete surgical excision is the standard of care for giant benign phyllodes tumors; axillary lymph node metastasis is rare, and dissection should be limited to patients with pathologic evidence of tumor in the lymph nodes. We report the case of a 40-year-old Mexican woman with giant mammary tumor who underwent a right total mastectomy. The pathology results showed a benign phyllodes tumor 4,857 g in weight and 40.2 × 36.3 × 15 cm in size. We do not suggest adjuvant radiation therapy for patients with benign phyllodes tumors that are widely excised. A review of the pertinent literature was performed.

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