Pharmaceuticals (Dec 2013)

Immunosuppressive Therapy in Immune-Mediated Liver Disease in the Non-Transplanted Patient

  • Anita Abhyankar,
  • Elliot Tapper,
  • Alan Bonder

DOI
https://doi.org/10.3390/ph7010018
Journal volume & issue
Vol. 7, no. 1
pp. 18 – 28

Abstract

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Autoimmune liver disease management goals are primarily slowing disease progression and symptomatic treatment. There are few options for curative medical management other than transplant for a spectrum of autoimmune liver disease that encompasses autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis as well as their overlap syndromes. These diseases are managed primarily with immunosuppressive therapy. Herein, we review the current literature, detailing the promise and pitfalls of the recommended immunosuppressive therapy for these challenging diseases.

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