Nature Communications (Jan 2018)

Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population

  • Noha A. Yousri,
  • Khalid A. Fakhro,
  • Amal Robay,
  • Juan L. Rodriguez-Flores,
  • Robert P. Mohney,
  • Hassina Zeriri,
  • Tala Odeh,
  • Sara Abdul Kader,
  • Eman K. Aldous,
  • Gaurav Thareja,
  • Manish Kumar,
  • Alya Al-Shakaki,
  • Omar M. Chidiac,
  • Yasmin A. Mohamoud,
  • Jason G. Mezey,
  • Joel A. Malek,
  • Ronald G. Crystal,
  • Karsten Suhre

DOI
https://doi.org/10.1038/s41467-017-01972-9
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

Read online

Blood metabolites are influenced by a combination of genetic and environmental factors. Here, Yousri and colleagues perform a whole-exome sequencing study in combination with a metabolomics analysis to identify metabolic quantitative trait loci in a Middle Eastern population.