Case Reports in Oncology (Sep 2013)

Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient

  • Sarah Pfrommer,
  • Achim Weber,
  • Philipp Dutkowski,
  • Niklaus G. Schäfer,
  • Beat Müllhaupt,
  • Jean-Pierre Bourquin,
  • Stefan Breitenstein,
  • Bernhard C. Pestalozzi,
  • Frank Stenner,
  • Christoph Renner,
  • Giannicola D'Addario,
  • Hans-Jörg Graf,
  • Alexander Knuth,
  • Pierre-Alain Clavien,
  • Panagiotis Samaras

DOI
https://doi.org/10.1159/000355320
Journal volume & issue
Vol. 6, no. 3
pp. 497 – 503

Abstract

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Pancreatic tumors are rare in children and adolescents. Here, we report the case of a 15-year-old boy who presented with a mixed acinar cell carcinoma/ductal adenocarcinoma with blastomatous components. He received multimodal treatment including various chemotherapy regimens and multistep surgery including liver transplantation. Introduction of FOLFIRINOX after relapse repeatedly achieved a durable metabolic and clinical response with good quality of life.

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