Nature Communications (Mar 2018)

The human cortex possesses a reconfigurable dynamic network architecture that is disrupted in psychosis

  • Jenna M. Reinen,
  • Oliver Y. Chén,
  • R. Matthew Hutchison,
  • B. T. Thomas Yeo,
  • Kevin M. Anderson,
  • Mert R. Sabuncu,
  • Dost Öngür,
  • Joshua L. Roffman,
  • Jordan W. Smoller,
  • Justin T. Baker,
  • Avram J. Holmes

DOI
https://doi.org/10.1038/s41467-018-03462-y
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 15

Abstract

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Temporal changes in brain dynamics are linked with cognitive abilities, but neither their stability nor relationship to psychosis is clear. Here, authors describe the dynamic neural architecture in healthy controls and patients with psychosis and find that they are stable over time and can predict psychotic symptoms.