Anaesthetic Management and Literature Review of Syndromic Craniosynostosis in Infants-A Case Series

Abstract

Craniosynostosis is a rare congenital defect. This group of patients is heterogeneous, presenting as a single suture defect in otherwise well child to Syndromic Craniosynostosis (SC) affecting multiple sutures as cranial defect associated with extracranial defects. Syndromic Craniosynostosis is found to be associated with Apert, Crouzon, Pfeiffer, Muenke and Saethre-Chotzen syndrome. These cases are generally associated with raised Intracranial Pressure (ICP), difficult airway and congenital multiple organ involvement. The case series describes the successful anaesthetic management of three and half-month-old male infant with Crouzon syndrome presented with raised ICP and difficult airway, planned for third ventriculostomy and seven-month-old male infant with Apert syndrome with syndactyly for correction surgery. A literature review about anaesthetic concerns related to SC is also described. The literature search was performed in the PubMed database with terms SC and anaesthetic management.

Keywords

• apert syndrome
• crouzon syndrome
• hydrocephalus
• raised intracranial pressure