PLoS Biology (Sep 2017)

The Experimental Design Assistant.

  • Nathalie Percie du Sert,
  • Ian Bamsey,
  • Simon T Bate,
  • Manuel Berdoy,
  • Robin A Clark,
  • Innes Cuthill,
  • Derek Fry,
  • Natasha A Karp,
  • Malcolm Macleod,
  • Lawrence Moon,
  • S Clare Stanford,
  • Brian Lings

DOI
https://doi.org/10.1371/journal.pbio.2003779
Journal volume & issue
Vol. 15, no. 9
p. e2003779

Abstract

Read online

Addressing the common problems that researchers encounter when designing and analysing animal experiments will improve the reliability of in vivo research. In this article, the Experimental Design Assistant (EDA) is introduced. The EDA is a web-based tool that guides the in vivo researcher through the experimental design and analysis process, providing automated feedback on the proposed design and generating a graphical summary that aids communication with colleagues, funders, regulatory authorities, and the wider scientific community. It will have an important role in addressing causes of irreproducibility.