Nature Communications (Aug 2022)

Microengineered devices enable long-term imaging of the ventral nerve cord in behaving adult Drosophila

  • Laura Hermans,
  • Murat Kaynak,
  • Jonas Braun,
  • Victor Lobato Ríos,
  • Chin-Lin Chen,
  • Adam Friedberg,
  • Semih Günel,
  • Florian Aymanns,
  • Mahmut Selman Sakar,
  • Pavan Ramdya

DOI
https://doi.org/10.1038/s41467-022-32571-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

Read online

Minimally invasive procedures for tracking neural activity are important for understanding of neural networks. Here the authors describe microfabricated implants and windows that enable long-term recordings of motor circuit activity in Drosophila, allowing them to watch how neurons change their structure and activity over weeks.