Gut-Expressed Vitellogenin Facilitates the Movement of a Plant Virus across the Midgut Wall in Its Insect Vector
Ya-Zhou He,
Yu-Meng Wang,
Tian-Yan Yin,
Wilmer J. Cuellar,
Shu-Sheng Liu,
Xiao-Wei Wang
Affiliations
Ya-Zhou He
Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and insects, Institute of Insect Sciences, Zhejiang University, Hangzhou, China
Yu-Meng Wang
Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and insects, Institute of Insect Sciences, Zhejiang University, Hangzhou, China
Tian-Yan Yin
Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and insects, Institute of Insect Sciences, Zhejiang University, Hangzhou, China
Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and insects, Institute of Insect Sciences, Zhejiang University, Hangzhou, China
Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and insects, Institute of Insect Sciences, Zhejiang University, Hangzhou, China
An essential step in the life cycle of many viruses is transmission to a new host by insect vectors, and one critical step in the transmission of persistently transmitted viruses is overcoming the midgut barrier to enter vectors and complete their cycle. Most viruses enter vector midgut epithelial cells via specific interaction between viral structural proteins and vector cell surface receptor complexes.
