Romanian Journal of Laboratory Medicine (Jan 2024)

Anti-thyroid peroxidase (TPO) antibodies – Comparative analysis of two automatic methods, ECLIA and CMIA

  • Manescu Ion Bogdan,
  • Luca Andreea,
  • Hutanu Adina,
  • Truta Andreea,
  • Dobreanu Minodora

DOI
https://doi.org/10.2478/rrlm-2024-0009
Journal volume & issue
Vol. 32, no. 1
pp. 33 – 40

Abstract

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Introduction: Anti-thyroid peroxidase autoantibodies (TPO) is an essential diagnostic tool for autoimmune disorders of the thyroid gland. However, TPO results are not always comparable due to differences between methods. Here, we aimed to investigate the differences between two modern laboratory methods for TPO measurement: electrochemiluminescence (ECLIA) and chemiluminescence microparticle (CMIA) immunoassays.

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