Nature Communications (Mar 2021)

Antibody-guided in vivo imaging of Aspergillus fumigatus lung infections during antifungal azole treatment

  • Sophie Henneberg,
  • Anja Hasenberg,
  • Andreas Maurer,
  • Franziska Neumann,
  • Lea Bornemann,
  • Irene Gonzalez-Menendez,
  • Andreas Kraus,
  • Mike Hasenberg,
  • Christopher R. Thornton,
  • Bernd J. Pichler,
  • Matthias Gunzer,
  • Nicolas Beziere

DOI
https://doi.org/10.1038/s41467-021-21965-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Invasive pulmonary aspergillosis is a life-threatening fungal lung disease devoid of specific rapid diagnosis and with limited therapeutic options. Here, the authors show how state-of-the-art imaging approaches can enable specific diagnosis and therapy monitoring of this infection.