Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z‑Arg-Lys-AOMK

• Jehad Almaliti,
• Momen Alhindy,
• Michael C. Yoon,
• Vivian Hook,
• Tadeusz F. Molinski,
• Anthony J. O’Donoghue,
• William H. Gerwick

Affiliations

Jehad Almaliti

Department Pharmaceutical Sciences, College of Pharmacy, The University of Jordan, Amman, Jordan

Momen Alhindy

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, United States

Michael C. Yoon

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States

Vivian Hook

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States

Tadeusz F. Molinski

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, United States

Anthony J. O’Donoghue

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States

William H. Gerwick

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, United States