Pifu-xingbing zhenliaoxue zazhi (Feb 2023)
A case of basal cell carcinoma of the penis misdiagnosed as extramammary Paget's disease
Abstract
A 83-year-old male presented with itchy plaques and nodules at the base of the penis for 9 years, and with ulceration for 3 years. Physical examination showed a dark red, 4.5 cm×2.5 cm plaque on the root of the penis, with scattered nodules and thick yellow-brown crust. Erythema, papules, erosions, and scales were also seen on the lower abdomen, groin, and scrotum. He was diagnosed with extramammary Paget's disease. Histopathology showed a large number of basophilic tumor lumps and contraction fissures between tumor and the peripheral tissues in the dermis. Tumor cell nuclei were large with dark stain, arranged in a palisade pattern around the tumor. The diagnosis was basal cell carcinoma. After resection of the plaque, the patient was treated with photodynamic therapy for 3 times, and followed up for 20 months with no recurrence.
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