Clinical Case Reports (Oct 2019)

Presumed antiphospholipid syndrome and thrombotic thrombocytopenic purpura: An infrequent association

  • Hallie Hanna Dolin,
  • Mark Dziuba,
  • Scott M. Pappada,
  • Thomas John Papadimos

DOI
https://doi.org/10.1002/ccr3.2416
Journal volume & issue
Vol. 7, no. 10
pp. 1984 – 1988

Abstract

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Abstract Antiphospholipid syndrome (APS) is an autoimmune disease that demonstrates antiphospholipid antibodies that cause hypercoagulability and leads to venous and arterial thrombosis. Autoantibodies to a disintegrin‐like and metalloprotease with thrombospondin type I motif, member 13 (ADAMTS 13) play a role in the microthrombosis of thrombotic thrombocytopenic purpura in APS patients.

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