Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting

• Christoph Gruber,
• Lea Krautner,
• Valter Bergant,
• Vincent Grass,
• Zhe Ma,
• Lara Rheinemann,
• Ariane Krus,
• Friederike Reinhardt,
• Lyupka Mazneykova,
• Marianne Rocha-Hasler,
• Dong-Jiunn Jeffery Truong,
• Gil Gregor Westmeyer,
• Andreas Pichlmair,
• Gregor Ebert,
• Florian Giesert,
• Wolfgang Wurst

Affiliations

Christoph Gruber

Institute of Developmental Genetics, Helmholtz Munich

Lea Krautner

Institute of Developmental Genetics, Helmholtz Munich

Valter Bergant

Technical University of Munich, School of Medicine and Health, Institute of Virology

Vincent Grass

Technical University of Munich, School of Medicine and Health, Institute of Virology

Zhe Ma

Institute of Virology, Technical University of Munich/Helmholtz Munich

Lara Rheinemann

Technical University of Munich, School of Medicine and Health, Institute of Virology

Ariane Krus

Institute of Developmental Genetics, Helmholtz Munich

Friederike Reinhardt

Institute of Developmental Genetics, Helmholtz Munich

Lyupka Mazneykova

Institute of Developmental Genetics, Helmholtz Munich

Marianne Rocha-Hasler

Institute of Virology, Technical University of Munich/Helmholtz Munich

Dong-Jiunn Jeffery Truong

Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich

Gil Gregor Westmeyer

Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich

Andreas Pichlmair

Technical University of Munich, School of Medicine and Health, Institute of Virology

Gregor Ebert

Institute of Virology, Technical University of Munich/Helmholtz Munich

Florian Giesert

Institute of Developmental Genetics, Helmholtz Munich

Wolfgang Wurst

Institute of Developmental Genetics, Helmholtz Munich