3β-Acetoxy-5α-cholestan-6-one 2-cyanoacetylhydrazone

Abstract

The asymmetric unit of the title compound, C32H51N3O3, consists of two crystallographically independent molecules, A and B; the 2-methylpentane group of molecule A and the propane group of molecule B are each disordered over two sets of sites, with refined site-occupancies of 0.825 (5):0.175 (5) and 0.630 (18):0.370 (18), respectively. In both molecules, the three cyclohexane rings in the steroid fused ring systems adopt chair conformations while the cyclopentane rings adopt envelope and twist conformations in molecules A and B, respectively. In the crystal, N—H...O and C—H...O hydrogen bonds link the two independent molecules together, generating R21(7) and R22(8) ring motifs.