THE INFLUENCE OF COORDINATION COMPOUNDS OF GERMANIUM (IV) WITH NITROBENZOIC AND CHLORBENZOICACIDS SALICYLALHYDRAZONES ON THE CONTENT OF THE BASIC LYMPHOCYTES POPULATIONS AND SUBPOPULATIONS IN THE COURSE OF INFLAMMATION IN MICE

Abstract

It was shown that in zymozan induced inflammation CD4/CD8 ratio increased for 1.8 times, that showed immune system activation. Also on the background of inflammation NK-cells content increased for 70%. Studied coordination compounds of germanium decrease the level of NK-cells and T-helpers but increase the level of T-suppressors that result in decreasing of CD4/CD8 ratio.

Keywords

• германій (iv)
• координаційні сполуки
• лімфоцити
• запалення