Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism

Takaaki Sakaue; Yosuke Okuno; Kosuke Mukai; Shingo Fujita; Junji Kozawa; Hitoshi Nishizawa; Taka-Aki Matsuoka; Hiromi Iwahashi; Maeda Norikazu; Yuto Yamazaki; Hironobu Sasano; Michio Otsuki; Iichiro Shimomura

doi:10.1155/2021/8860498

Case Reports in Endocrinology (Jan 2021)

Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism

Takaaki Sakaue,
Yosuke Okuno,
Kosuke Mukai,
Shingo Fujita,
Junji Kozawa,
Hitoshi Nishizawa,
Taka-Aki Matsuoka,
Hiromi Iwahashi,
Maeda Norikazu,
Yuto Yamazaki,
Hironobu Sasano,
Michio Otsuki,
Iichiro Shimomura

Affiliations

Takaaki Sakaue: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Yosuke Okuno: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Kosuke Mukai: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Shingo Fujita: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Junji Kozawa: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Hitoshi Nishizawa: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Taka-Aki Matsuoka: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Hiromi Iwahashi: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Maeda Norikazu: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Yuto Yamazaki: Department of Pathology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan
Hironobu Sasano: Department of Pathology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan
Michio Otsuki: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Iichiro Shimomura: Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan

DOI: https://doi.org/10.1155/2021/8860498
Journal volume & issue: Vol. 2021

Abstract

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A 67-year-old Japanese woman who had end-stage renal disease was referred to our hospital for kidney transplantation. Abdominal CT revealed a large adrenal mass with inhomogeneity. She had a history of hospitalization for stroke and heart failure and exhibited prominent hyporeninemic hyperaldosteronism. Histological examination of the resected tumor with anti-CYP11B2 antibody indicated that she had a vascular endothelial cyst with primary aldosteronism (PA) due to multiple adrenocortical micronodules. This report implicates the pathological interaction between adrenal vascular cysts and PA-mediated vascular damage of the adrenal vein.

Published in Case Reports in Endocrinology

ISSN: 2090-6501 (Print); 2090-651X (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://onlinelibrary.wiley.com/journal/7520

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