npj Digital Medicine (2020-07-01)

Wearable devices can predict the outcome of standardized 6-minute walk tests in heart disease

  • Charlotte Schubert,
  • Gareth Archer,
  • Jo M. Zelis,
  • Sarah Nordmeyer,
  • Kilian Runte,
  • Anja Hennemuth,
  • Felix Berger,
  • Volkmar Falk,
  • Pim A. L. Tonino,
  • Rod Hose,
  • Herman ter Horst,
  • Titus Kuehne,
  • Marcus Kelm

Journal volume & issue
Vol. 3, no. 1
pp. 1 – 9


Read online

Abstract Wrist-worn devices with heart rate monitoring have become increasingly popular. Although current guidelines advise to consider clinical symptoms and exercise tolerance during decision-making in heart disease, it remains unknown to which extent wearables can help to determine such functional capacity measures. In clinical settings, the 6-minute walk test has become a standardized diagnostic and prognostic marker. We aimed to explore, whether 6-minute walk distances can be predicted by wrist-worn devices in patients with different stages of mitral and aortic valve disease. A total of n = 107 sensor datasets with 1,019,748 min of recordings were analysed. Based on heart rate recordings and literature information, activity levels were determined and compared to results from a 6-minute walk test. The percentage of time spent in moderate activity was a predictor for the achievement of gender, age and body mass index-specific 6-minute walk distances (p < 0.001; R 2 = 0.48). The uncertainty of these predictions is demonstrated.