Nature Communications (Dec 2018)

Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION 2

  • Daniel J. Gibbs,
  • Hannah M. Tedds,
  • Anne-Marie Labandera,
  • Mark Bailey,
  • Mark D. White,
  • Sjon Hartman,
  • Colleen Sprigg,
  • Sophie L. Mogg,
  • Rory Osborne,
  • Charlene Dambire,
  • Tinne Boeckx,
  • Zachary Paling,
  • Laurentius A. C. J. Voesenek,
  • Emily Flashman,
  • Michael J. Holdsworth

DOI
https://doi.org/10.1038/s41467-018-07875-7
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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VRN2 is a Polycomb Repressive Complex 2 subunit, best known as a regulator of vernalization that accumulates during prolonged cold. Here Gibbs et al. show that VRN2 is degraded via the N-end rule pathway, which prevents ectopic accumulation of VRN2 in the absence of appropriate environmental stimuli.