Advancements in BaTiO3-Based Ultrasound‐Triggered Piezoelectric Catalysis for Tumor Therapy

Abstract

Barium titanate (BaTiO3), as an emerging inorganic piezoelectric material with excellent piezoelectric catalytic effects, has showing advantages in tumor therapy. To achieve ultrasound-regulated tumor treatment using BaTiO3, researchers have developed strategies including utilizing BaTiO3 combined with ultrasound for tumor therapy, enhancing reactive oxygen species (ROS) generation through chemical modification of BaTiO3, and employing combined therapy with other treatment methods. These strategies provide new insights and approaches for non-invasive and precision treatment of tumors. In this review, we first explain the principle of piezoelectric effect based on BaTiO3. Subsequently, we introduce the application of BaTiO3 as a piezoelectric material in tumor therapy and its combined therapy with other treatment modalities in tumor treatment. Finally, we summarize the current status and limitations of BaTiO3 in ultrasound‐triggered piezoelectric therapy for tumors and propose future prospects.

Keywords

• |barium titanate|ultrasound|piezoelectric catalysis|tumor therapy