Synthesis, characterization and anticandidal activity of dioxomolybdenum(VI) complexes of the type [MoO2{ON=C(CH3)Ar}2] and [MoO2{OC(R)CHC(R’)=NC6H5}2]

Abstract

Interaction of [MoO2(acac)2] with internally functionalized oximes like HON=C(CH3)Ar (Ar = C4H3S, C4H3O or C5H4N) and Schiff's Bases derived from β – diketones like HOC(R)CHC(R′)=NC6H5 (R = R’ = CH3 or C6H5; R = CH3 and R’ = C6H5) led to the formation of yellow dioxomolybdenum(VI) complexes of the type [MoO2{ON=C(CH3)Ar}2] and [MoO2{OC(R)CHC(R′)=NC6H5}2]. Oximes were synthesized by green methodology. The newly synthesized complexes were characterized on basis of elemental analysis and various spectral findings.Anticandidal activity of [MoO2{ON=C(CH3)C6H4N}2] clearly reveals that the complex is biologically active against fungal diseases.

Keywords

• Organic chemistry
• Inorganic chemistry
• Dioxomolybdenum(VI) complexes
• Internally functionalized oximes
• Schiff's bases derived from β – diketones