Higher levels of total pepsin and bile acids in the saliva as a possible risk factor for early laryngeal cancer

Abstract

Background. Gastroesophageal reflux is suspected to be an etiological factor in laryngeal and pharyngeal cancer. The aim of this study was to establish, using a non-invasive method, whether laryngopharyngeal reflux (LPR) appears more often in patients with early laryngeal cancer than in a control group.

Keywords

• laryngopharyngeal reflux
• gastric acid
• pepsin
• bile acids
• laryngeal carcinoma