Вестник хирургии имени И.И. Грекова (Jan 2018)
ADVANTAGES AND DISADVANTAGES OF WARFARIN AND PRADAXA THERAPY FOR VENOUS THROMBOEMBOLISM
Abstract
An analysis of complex examination of 110 patients with venous thromboembolism was made. The patients were separated into 2 groups. The first group included 60 patients, who had the start heparin therapy during 7 days with the following 6-month warfarin therapy. Warfarin was substituted by pradaxa (dabigatran) for 50 patients of the second group. The efficacy of pradaxa could be compared with warfarin. However, pradaxa had a number of advantages such as the predictable anticoagulant effect, standard dosages. This medicine is more predictable and doesn’t require a control of homeostasis and an adjustment of drug dosage.
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