Frontiers in Child and Adolescent Psychiatry (Jul 2025)

Interactive effects of prenatal adversity and COVID-19 hardship on youth psychological distress: a longitudinal study

  • Yifan Wang,
  • Yifan Wang,
  • Xinni Wang,
  • Chloé Voyer,
  • Alain Brunet,
  • François Freddy Ateba,
  • Ashley Wazana,
  • Ashley Wazana,
  • David P. Laplante

DOI
https://doi.org/10.3389/frcha.2025.1581135
Journal volume & issue
Vol. 4

Abstract

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IntroductionThe COVID-19 pandemic resulted in severe loss of life and increased anxiety as well as fear worldwide. This study explored whether pre-pandemic exposure to varying levels of perinatal maternal adversity coupled with pandemic-related experiences are related to youth distress levels.MethodsData from 119 youth (aged 9–17) and their mothers were analyzed to assess the interactive effects of perinatal maternal adversity and pandemic-related objective hardship on youth psychological distress.ResultsYouth-reported hardship models consistently explained more variance in their psychological distress. Youth-reported hardship, specifically daily life changes, predicted psychological distress, including PTSD symptoms and peritraumatic experiences during the pandemic.DiscussionYouths exposed to high perinatal maternal socio-environmental adversity demonstrated resilience when faced with pandemic disruptions, suggesting that alignment between early adversity and later stress can mitigate distress during crises.

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