Acoustic Multi-Detection of Gliadin Using QCM Crystals Patterned with Controlled Sectors of TEM Grid and Annealed Nanoislands on Gold Electrode
Giuliocesare Casari Bariani,
Lan Zhou,
Simone Poggesi,
Rakesh Mittapalli,
Marisa Manzano,
Rodica Elena Ionescu
Affiliations
Giuliocesare Casari Bariani
Laboratoire Lumière, Nanomatériaux et Nanotechnologies – L2n, Université de Technologie de Troyes, CNRS ERL 7004, 12 rue Marie Curie, CS 42060, 10004 Troyes CEDEX, France
Lan Zhou
Laboratoire Lumière, Nanomatériaux et Nanotechnologies – L2n, Université de Technologie de Troyes, CNRS ERL 7004, 12 rue Marie Curie, CS 42060, 10004 Troyes CEDEX, France
Simone Poggesi
Laboratoire Lumière, Nanomatériaux et Nanotechnologies – L2n, Université de Technologie de Troyes, CNRS ERL 7004, 12 rue Marie Curie, CS 42060, 10004 Troyes CEDEX, France
Rakesh Mittapalli
Laboratoire Lumière, Nanomatériaux et Nanotechnologies – L2n, Université de Technologie de Troyes, CNRS ERL 7004, 12 rue Marie Curie, CS 42060, 10004 Troyes CEDEX, France
Marisa Manzano
Dipartimento di Scienze Agroalimentari, Ambientali e Animali (DI4A), Università degli Studi di Udine, Via Sondrio 2/A, 33,100 Udine, Italy
Rodica Elena Ionescu
Laboratoire Lumière, Nanomatériaux et Nanotechnologies – L2n, Université de Technologie de Troyes, CNRS ERL 7004, 12 rue Marie Curie, CS 42060, 10004 Troyes CEDEX, France
Celiac diseases are a group of gluten ingestion-correlated pathologies that are widespread and, in some cases, very dangerous for human health. The only effective treatment is the elimination of gluten from the diet throughout life. Nowadays, the food industries are very interested in cheap, easy-to-handle methods for detecting gluten in food, in order to provide their consumers with safe and high-quality food. Here, for the first time, the manufacture of controlled micropatterns of annealed gold nanoislands (AuNIs) on a single QCM crystal (QCM-color) and their biofunctionalization for the specific detection of traces of gliadin is reported. In addition, the modified quartz crystal with a TEM grid and 30 nm Au (Q-TEM grid crystal) is proposed as an acoustic sensitive biosensing platform for the rapid screening of the gliadin content in real food products.
