Nature Communications (Nov 2021)

The main oxidative inactivation pathway of the plant hormone auxin

  • Ken-ichiro Hayashi,
  • Kazushi Arai,
  • Yuki Aoi,
  • Yuka Tanaka,
  • Hayao Hira,
  • Ruipan Guo,
  • Yun Hu,
  • Chennan Ge,
  • Yunde Zhao,
  • Hiroyuki Kasahara,
  • Kosuke Fukui

DOI
https://doi.org/10.1038/s41467-021-27020-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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Auxin inactivation plays important roles in plant development. Here the authors show that the main route of IAA inactivation in Arabidopsis is via conjugation by GH3 IAA-amidosynthetases followed by DAO1 dioxygenase-mediated oxidation of the conjugated forms and hydrolysis by ILR1 to release inactive oxIAA.