Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis
Baxter-Parker Gregory,
Gaddam Ravinder Reddy,
Moltchanova Elena,
Carr Anitra,
Shaw Geoff,
Chambers Stephen,
Gieseg Steven P.
Affiliations
Baxter-Parker Gregory
School of Biological Sciences, University of Canterbury, Christchurch, New Zealand
Gaddam Ravinder Reddy
Division of Cardiovascular Medicine, Department of Internal Medicine, Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
Moltchanova Elena
Department of Mathematics and Statistics, University of Canterbury, Christchurch, New Zealand
Carr Anitra
Department of Pathology & Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand
Shaw Geoff
Department of Intensive Care, Christchurch Hospital, New Zealand
Chambers Stephen
Department of Pathology & Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand
Gieseg Steven P.
School of Biological Sciences, University of Canterbury, Christchurch, New Zealand
Introduction: Neopterin and 7,8-dihydroneopterin are used as biomarkers of oxidative stress and inflammation, but the effect of kidney function on these measurements has not been extensively explored. We examine the levels of oxidative stress, inflammation and kidney function in intensive patients and compare them to equivalent patients without sepsis.
