Nature Communications (Aug 2018)

De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments

  • Matthew J. Lee,
  • Judith Mantell,
  • Ian R. Brown,
  • Jordan M. Fletcher,
  • Paul Verkade,
  • Richard W. Pickersgill,
  • Derek N. Woolfson,
  • Stefanie Frank,
  • Martin J. Warren

DOI
https://doi.org/10.1038/s41467-018-05922-x
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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Bacterial microcompartments (BMCs) are protein-bound organelles encapsulating segments of metabolic pathways. Here the authors utilize specific de novo coiled-coil protein-protein interactions to display proteins on the outer or inner surface of BMCs.