Biocompatibility of acrylic resin after being soaked in sodium hypochlorite

Dental Journal: Majalah Kedokteran Gigi. 2009;42(2):94-98 DOI 10.20473/j.djmkg.v42.i2.p94-98

 

Journal Homepage

Journal Title: Dental Journal: Majalah Kedokteran Gigi

ISSN: 1978-3728 (Print); 2442-9740 (Online)

Publisher: Universitas Airlangga

LCC Subject Category: Medicine: Dentistry

Country of publisher: Indonesia

Language of fulltext: Indonesian, English

Full-text formats available: PDF

 

AUTHORS


Nike Hendrijatini (Department of Prosthodontic, Faculty of Dental Medicine, Universitas Airlangga)

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 16 weeks

 

Abstract | Full Text

<span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Background: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Acrylic resin as basic material for denture will stay on oral mucosa for a very long time. The polymerization of acrylic </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>resin can be performed by conventional method and microwave, both produce different residual monomer at different toxicity. Acrylic resin </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>can absorb solution, porous and possibly absorb disinfectantt as well, that may have toxic reaction with the tissue. Sodium Hypochlorite </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>as removable denture disinfectant can be expected to be biocompatible to human body. The problem is how biocompatible acrylic resin </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>which has been processed by conventional method and microwave method after being soaked in sodium hypochlorite solution. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Purpose: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The aim of this study was to understand in vitro biocompatibility of acrylic resin which has polimerated by conventional method and </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>microwave after being soaked in sodium hypochlorite using tissue culture. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Methods: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Four groups of acrylic resin plate were produced, </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>the first group was acrylic resin plate with microwave polymeration and soaked in sodium hypochlorite, the second group was acrylic </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>resin plate with microwave polymeration but not soaked, the thirdwas one with conventional method and soaked and the last group </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>was one with conventional method but not soaked, and in 1 control group. Each group consists of 7 plates. Biocompatibility test was </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>performed in-vitro on each material using fibroblast tissue culture (BHK-21 cell-line). </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Result: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The percentage between living cells </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>and dead cells from materials which was given acrylic plate was wounted. The data was analyzed statistically with T test. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Conclusion: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The average value of living cells is higher in acrylic resin poimerization using microwave method compared to conventional method, </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>in both soaked and non soaked (by sodium hypochlorite) group. This means that sodium hypochlorite 0.5% was biocompatible to the </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>mouth mucosa as removable denture disinfectant for 10 minutes soaking and washing afterwards.</em></span></span></span></span></span></span></span></span></span></span></span></span></span></span><br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px;" /></span></span></span></span></span></span></span></span>