A genetic toolkit and gene switches to limit Mycoplasma growth for biosafety applications

Alicia Broto; Erika Gaspari; Samuel Miravet-Verde; Vitor A. P. Martins dos Santos; Mark Isalan

doi:10.1038/s41467-022-29574-0

Nature Communications (Apr 2022)

A genetic toolkit and gene switches to limit Mycoplasma growth for biosafety applications

Alicia Broto,
Erika Gaspari,
Samuel Miravet-Verde,
Vitor A. P. Martins dos Santos,
Mark Isalan

Affiliations

Alicia Broto: Department of Life Sciences, Imperial College London
Erika Gaspari: Laboratory of Systems and Synthetic Biology, Wageningen University & Research
Samuel Miravet-Verde: Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr Aiguader 88
Vitor A. P. Martins dos Santos: Laboratory of Systems and Synthetic Biology, Wageningen University & Research
Mark Isalan: Department of Life Sciences, Imperial College London

DOI: https://doi.org/10.1038/s41467-022-29574-0
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 13

Abstract

Read online

Mycoplasmas are minimal cell model organisms but lack genetic tools. Here the authors provide a robust genetic toolkit for Mycoplasma demonstrating gene circuit engineering applications.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal