Prospects for therapy aimed at restoring the beta-cell pool in patients with diabetes mellitus (review of the literature)

Abstract

The authors review results of evaluation of possibility, safety and prospects of regenerative therapy aimed at restoring beta-cell pool in diabetes mellitus. A detailed analysis of sources of new beta-cells is presented, reparation mechanisms and factors contributing to regeneration are discussed.

Keywords

• diabetes mellitus
• regeneration
• beta-cells