SEMA4D acts as a novel oligogenic pathogenic gene of idiopathic hypogonadotropic hypogonadism through the PlexinB1/MET/RND1/RHOA/RAF1/MAPK signaling axis

• Daoqi Wang,
• Yonghua Niu,
• Jiahong Tan,
• Jiaxin Wang,
• Le Ling,
• Yinwei Chen,
• Jianan Gong,
• Hao Xu,
• Qing Ling,
• Jianhe Liu,
• Jihong Liu

Affiliations

Daoqi Wang

Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650033, China; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Yonghua Niu

Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Wuhan, Hubei 430030, China

Jiahong Tan

Department of Obstetrics and Gynecology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650034, China

Jiaxin Wang

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Le Ling

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Yinwei Chen

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Jianan Gong

Department of Urology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150007, China

Hao Xu

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Qing Ling

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Jianhe Liu

Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650033, China

Jihong Liu

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China; Corresponding author. Tongji Hospital, Huazhong University of Science and Technology, No. 1095, Jiefang Avenue, Wuhan, Hubei 430030, China.